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產(chǎn)品名稱:Rabbit Anti-ZXDC antibody
反應(yīng): (predicted: Human,Mouse,Rat,Rabbit,Sheep,Cow)
免疫原:KLH conjugated synthetic peptide derived from human ZXDC
保存:-20℃
保質(zhì)期:1年
單克隆抗體
產(chǎn)品名稱:Anti-ZXDC antibody
Mouse Anti-ZXDC
免疫原:KLH conjugated synthetic peptide derived from human ZXDC
保存:-20℃
保質(zhì)期:1年
Zinc finger X-linked duplicated family member C (ZXDC) is an 858 amino acid protein belonging to the ZDX family. Localized to the nucleus, ZDXC is expressed at high levels in heart, kidney, liver and testis, with lower levels of expression in lung, muscle, placenta, small intestine and spleen. ZDXC, with ZDXA, forms a complex that binds to the class II trans-activator (CIITA). CIITA, like the X1-binding regulatory factor X (RFX) complex and the nuclear factor Y (NFY) complex, is a transcriptional co-factor that is necessary, but not sufficient, for major histocompatibility complex (MHC) class II gene transcription. ZXDC, by regulating CIITA function, activates the transcription of MHC genes.
Recombinant human ZXDC
SERH2790; UNQ2790; Zinc finger protein ZXDC; ZXD family zinc finger C; ZXD like zinc finger protein; ZXD-like zinc finger protein; Zxdc; ZXDC_HUMAN; ZXDL.
應(yīng)用:SDS-PAGE,Western blot,ELISA
Biological activity,immunology research
Zinc finger X-linked duplicated family member C (ZXDC) is an 858 amino acid protein belonging to the ZDX family. Localized to the nucleus, ZDXC is expressed at high levels in heart, kidney, liver and testis, with lower levels of expression in lung, muscle, placenta, small intestine and spleen. ZDXC, with ZDXA, forms a complex that binds to the class II trans-activator (CIITA). CIITA, like the X1-binding regulatory factor X (RFX) complex and the nuclear factor Y (NFY) complex, is a transcriptional co-factor that is necessary, but not sufficient, for major histocompatibility complex (MHC) class II gene transcription. ZXDC, by regulating CIITA function, activates the transcription of MHC genes.
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